PrenatalSafe Complete

What's Included?

• PrenatalSafe Karyo and Genesafe Complete.
• Includes screening for;
• Inherited gene disorders;
• Cystic Fibrosis
• Deafness autosomal recessive type 1A
• Deafness autosomal recessive type 1B
• Thalassemia-Beta
• Sickle cell anaemia
• Non- Inherited (De Novo);
• 25 genes screened for 44 different genetic disorders​
• Gender Determination (optional)  

PrenatalSafe Complete is composed of two screens: PrenatalSafe Karyo and Genesafe Complete. Please note this test does NOT include the Microdeletion Syndromes. But it is combined with the additional Genesafe Complete screen for Inherited and Non-Inherited (De Novo) features that can identify conditions which may have otherwise gone undetected until after the baby’s birth.

Many of these disorders are not typically associated with abnormal ultrasound findings (especially in the first trimester) or may not be evident until the late second or third trimester, when diagnostic invasive testing can pose a risk of preterm birth, or after delivery.

Family history is not always a good indicator of risk for these conditions, which are commonly caused by De- Novo genetic disorders. 

These 25 genes are screened for 44 different genetic disorders - Read here. The five Mutations in these 25 genes are known to cause skeletal dysplasia, congenital heart defects, multiple congenital malformation syndromes, multiple congenital anomalies, autism, epilepsy, and intellectual disability.

This test also offers a buccal (check) swab sample from the baby’s father to screen for non- inherited conditions, this is purely voluntary and does not include paternity analysis

Inherited gene disorders include;

• Cystic Fibrosis
• Deafness autosomal recessive type 1A
• Deafness autosomal recessive type 1B
• Thalassemia-Beta
• Sickle cell anaemia

Taken from 10 weeks, it is suitable for single and *twin pregnancies. *Only the presence or absence of the Y chromosome can be reported in twins.

Results from 15 Working Days. Processed within the EU.