PrenatalSafe Karyo PLUS

Routine NHS screening takes place between 12 and 14 weeks Many families opt for NIPT testing as it can be taken as early as 10 weeks and, is a more detailed and complementary screening tool for many genetic disorders that are not routinely analysed with current NHS technology. 

NIPT provides you with a clearer picture of the risk of your pregnancy being affected by a chromosome abnormality or single genetic disorder.

What's Included?

• Prenatalsafe Karyo
• Downs Syndrome (Trisomy 21)
• Patau’s Syndrome (Trisomy 13) 
• Edwards Syndrome (Trisomy 18)
• Sex Chromosomes - X & Y
• Trisomy 9
• Trisomy 16
• RAA's
• Deletions and Duplications in any chromosome. These are missing or gained pieces of chromosomes (>7Mb)

• Gender Determination (optional)

9 different Microdeletion syndromes:

• 1p36 (1p36 deletion syndrome)
• 4p- (Wolf-Hirschhorn syndrome)
• 5p-(Cri-du-Chat syndrome)
• 15q11.2 (Prader-Willi / Angelman syndrome)
• 22q11.2 (DiGeorge syndrome)
• q24 (Langer-Giedion syndrome)
• 1q23 (Jacobsen syndrome)
• 17p11.2 (Smith-Magenis syndrome)

Prenatalsafe Karyo Plus includes everything in Prenatalsafe Karyo, screening all 24 chromosomes, including chromosomes 9 and 16 and also goes one step further and detects for 9 microdeletion syndromes.  With Prenatalsafe Karyo Plus, you can have peace of mind knowing that you have valuable information about your growing baby's health.

The ability to identify these important chromosomal causes of miscarriage can help with monitoring and management of this and subsequent pregnancies.

More info on: Trisomy 9: is a chromosomal condition where the vast majority result in miscarriage in the 1st trimester. Unfortunately, the majority of babys that are born alive, will not survive during early life and those that do, usually have a varying severity of health concerns, including intellectual disability and cardiac defects.

Trisomy 16: Is the most commonly occurring autosomal trisomy seen in first trimester miscarriages. Rare survivors with mosaic trisomy 16 are at increased risk for health concerns including intra-uterine growth restriction (IUGR) during pregnancy, intellectual disability, and cardiac defects. Trisomy 16 has been found to be the most common genetic link to autism. Sadly, of all trisomy’s, 16 seems to be the most common, occurring in approximately one percent of all pregnancies. and accounting for around 16 % of miscarriages.

This test is suitable for single and *twin pregnancies

*Only the presence or absence of the Y chromosome can be reported in twins.

Results from 10 Working Days. Processed within the EU.